Macbecin II was identified as a compound that upregulates MHC-I expression, enhancing immune-mediated cancer cell killing. In ...

This study makes the fundamental discovery of the first natural animal rhodopsin that uses a chloride ion instead of an amino acid side chain as a counterion. Using a combination of biochemical and ...

ASO delivery and efficacy was first optimized by targeting cardiac troponin T in cardiac iPS-derived organoids: loss of rhythmic contraction in more than 90% of transfected organoids was achieved.

This study provides important insights into the regulation of type-I interferon signaling and anti-tumor immunity, demonstrating that ORMDL3 promotes RIG-I degradation to suppress immune responses.

Priyom Bose holds a PhD in plant biology and biotechnology from the University of Madras, India. She is an experienced academic researcher and science writer. Priyom has co-authored several original ...