Damage to the cell wall can lead to vacuole rupture and cell death. A conserved mechanism involving ATG8ylation, where ATG8 is relocated to the vacuole membrane, helps protect against this.

How then does the tonoplast increase its surface area so that the vacuole can quickly expand (Figure 2)? Scientists still know very little about this dynamic process, and they are actively ...

The findings were published in Nature Plants. The research team showed that ATG8, which is normally located in small cellular vesicles that mediate autophagy, is quickly relocated to the vacuole ...