All linearized viral DNA and plasmids were precipitated with ethanol/NaAc as per the above description ... The cells were then incubated with anti-PCV2 capsid MAb (RTI, PA, United States) for 2 h at ...

Next to the viral capsid, also the cargo, i.e., the recombinant genome consisting of the transgene expression cassette flanked by the ITRs, offers multiple opportunities for engineering and ...

Ultimately, the virus uses our body's machinery to produce copies of itself and spread infection. The HIV-1 capsid is formed by a mesh of around 200 protein hexamers and pentamers, arranged ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Once inside human cells, HIV integrates the viral genome into that of the human host. Ultimately, the virus uses our body’s machinery to produce copies of itself and spread infection. The HIV-1 capsid ...

Pseudoscience has recently re-emerged in the U.S. While much of it concerns vaccines, an "oldie" is again making the rounds: ...

Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

(THE CONVERSATION) In the last few months, schools all over the country have closed because of outbreaks of norovirus. Also known as stomach flu, norovirus infections cause watery diarrhea, low-grade ...