Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Deregulation of the mechanisms regulating aldosterone biosynthesis results in primary aldosteronism (PA), the most common form of secondary hypertension with an estimated prevalence of about 10% in ...

A vet explains everything to know about Cushing's disease in dogs, from first signs to treatment, and how to care for your ...

Glucose and insulin tolerance tests were performed at the end of each week and blood and urine collected for measurements of plasma aldosterone, renin activity, electrolytes, insulin, and lipoproteins ...

Ayres, P. J., Hechter, O., Saba, N., Simpson, S. A., and Tait, J. F., Biochem. J., 65, 22, P (1956).

PDEs also play an important role in the regulation of the renin-angiotensin-aldosterone system (RAAS), a key endocrine mechanism that controls blood pressure and fluid balance in the body (26, 27). In ...

Hypertension is a major global health issue. Aldosterone synthase inhibitors (ASIs) have emerged as a promising therapeutic strategy for blood pressure control. A thorough search of the MEDLINE and ...

The symptoms of hyperkalemia begin with muscle weakness. As serum potassium levels rise, symptoms progress to more significant muscle twitching, weakness, nausea, and cramping. [69] Cardiac ...

Addison’s disease is a rare autoimmune disorder where the adrenal glands don’t produce enough vital hormones, causing fatigue, weight loss, low blood pressure, and potential life-threatening crises if ...

Glucocorticoids are one of three groups of hormones (including mineralocorticoids and androgens) produced in the adrenal ... occurring mineralocorticoid is aldosterone – it’s primary function ...

Experts call them circadian rhythms. The times that dictate the 24 hours of the human organism are in practice, with ...