Recently, my brother’s six-year-old pug, Ellie, began having accidents in the house. After a few weeks of the onset of what ...

At present, oral xanthine oxidase inhibitors (“XOIs”) are the preferred therapeutic option used to inhibit the production of uric acid and decrease high uric acid levels in gout patients. Allopurinol ...

Allopurinol and its principal metabolic product, oxipurinol (alloxanthine, oxoallopurinol), inhibit the enzyme, xanthine oxidase, that normally converts hypoxanthine to xanthine, and xanthine to ...

Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education; National Research & Development Center of Apple Processing Technology; College of ...

In the present experiments the effects on insulin secretion of theophylline, a methyl xanthine derivative which inhibits cyclic nucleotide phosphodiesterase 6 and increases the intracellular ...

Department of Materials Science and Metallurgy, University of Cambridge, 27 Charles Babbage Road, Cambridge, CB3 0FS, United Kingdom ...