Age-related macular degeneration (AMD) primarily affects the elderly, impacting central vision essential for daily activities ...

Because the cornea is an avascular, low-cell-density tissue that relies on aqueous humor circulation to maintain metabolism, ...

Completed Phase 2 enrollment with randomization of 51 subjects into treatment and control armsPhase 1/2 study (N=60) demonstrated favorable safety and tolerability profile with no serious adverse even ...

A research team from the Eye & ENT Hospital of Fudan University, China, has developed a novel biocompatible nanoadhesive for ...

A 65-year-old female patient with type 2 diabetes mellitus and hypercholesterolemia presented with moderately graded nonproliferative diabetic retinopathy with widespread hard exudates (HEs) in the ...

Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China Hubei Province Key Laboratory of Molecular Imaging, Wuhan ...

Corneal neovascularization (CNV) occurs when abnormal blood vessels grow into the cornea in response to ischemic or hypoxic conditions caused by infections, inflammation or chemical injuries. CREB ...

Once diagnosed, patients should be followed and monitored for development of subretinal neovascularization, known as proliferative MacTel. Subretinal neovascularization can result in significant ...

In certain retinal diseases, the activated microglia promote retinal angiogenesis in hypoxia stress through neurovascular coupling and guide neovascularization to avascular areas (e.g., the outer ...

Purpose: The purpose of this study was to explore the potential underlying mechanism of anti-vascular effects of peroxisome proliferator–activated receptor α (PPARα) agonist fenofibrate against ...

NLRP3 inflammasome activation and complement-mediated inflammation have been implicated in promoting choroidal neovascularization (CNV) in age-related macular degeneration (AMD), but central questions ...