The EASI-ORC pipeline provides a robust toolset for the analysis of fluorescent microscopy images of yeast for mRNA-organelle colocalization. An accompanying step-by-step user guide allows for ...

This effectively solves the problem of the final helix. Left: Short-tailed proteins (red) were successfully woven into the cellular membrane, reaching the membrane of the lysosome organelle (green); ...

Moreover, these proteins were unable to arrive at their proper destination—a cellular organelle in which they are supposed to function—and were found instead inside another organelle that handles ...

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China College of Materials Science and Optoelectronic ...

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is commonly known to be responsible for protein trafficking and secretion.

Invaginations of the nuclear membrane occur in different shapes, sizes, and compositions. Part of these pleiomorphic invaginations make up the nucleoplasmic reticulum (NR), while others are merely ...

Although high-throughput techniques facilitate identification of novel contact sites (e.g., organelle-organelle and organelle-vesicle interactions), little is known about their impact on cellular ...