CALR mutations occur in about 20% of patients with primary and post-essential thrombocythemia myelofibrosis, as per the study ...

This is the third indication under clinical development for soquelitinib, which is also in a registrational Phase 3 trial for peripheral T cell lymphoma (PTCL) and a Phase 1 trial for atopic ...

Lucknow: Doctors at Rae Bareli AIIMS have successfully performed a rare and complex surgery on a youth suffering from ...

Splenic torsion is a very rare condition, with splenomegaly and recent birth as known possible risk factors. We report the case of a woman with known splenomegaly, who presented with left-sided ...

Portal hypertension may not be associated with any clinical abnormalities but is usually accompanied by splenomegaly, esophageal varices, ascites or symptoms resulting from shunting of venous ...

Regulatory submission includes data from pivotal trials addressing key clinical manifestations of myelofibrosis, namely splenomegaly, constitutional symptoms and anemia. SIMPLIFY-1 was a global ...

Here we describe 5 patients from 2 unrelated kindreds with bi-allelic mutations in IRAK4, where one of which was a missense mutation, resulting in a severe autoinflammatory phenotype without overt ...