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Somatostatin - Wikipedia
Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin ...
Somatostatin: What It Is, Function & Symptoms - Cleveland Clinic
Somatostatin is an important hormone that works to inhibit the release of other hormones. It also regulates the activity of your gastrointestinal tract and prevents the rapid reproduction of cells. What is somatostatin?
Physiology, Somatostatin - StatPearls - NCBI Bookshelf
2023年7月24日 · Somatostatin is a cyclic peptide well known for its strong regulatory effects throughout the body. Also known by the name of growth hormone inhibiting hormone, it is produced in many locations, which include the gastrointestinal (GI) tract, pancreas, hypothalamus, and central nervous system (CNS).
Somatostatin | Hormones
Somatostatin from the hypothalamus inhibits the pituitary gland’s secretion of growth hormone and thyroid stimulating hormone. In addition, somatostatin is produced in the pancreas and inhibits the secretion of other pancreatic hormones such as insulin and glucagon.
The role of neuropeptide somatostatin in the brain and its
2021年3月19日 · Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein marker of...
Somatostatin: Uses, Interactions, Mechanism of Action
2015年9月16日 · Somatostatin is a natural peptide hormone used to treat acute bleeding from esophageal varices, gastrointestinal ulcers, and gastritis; prevent pancreatic complications after surgery; and restrict secretions of the upper intestine, pancreas, and biliary tract.
Somatostatin - Structure - Function - TeachMePhysiology
2023年7月17日 · Somatostatin (SS) is a polypeptide hormone with numerous inhibitory roles in the body. SS was initially identified as a product of hypothalamic neurones but has been found to be a secretory product of cells in the stomach, duodenum and the central nervous system.
Somatostatin - an overview | ScienceDirect Topics
Somatostatin is a naturally occurring polypeptide hormone that is widely distributed throughout the human central nervous system and peripheral tissues. It has inhibitory effects on neurotransmission and secretion, and it also regulates the …
Somatostatin | Hormone Regulation, Neuroendocrine Control
Somatostatin, polypeptide that inhibits the activity of certain pancreatic and gastrointestinal hormones. Somatostatin exists in two forms: one composed of 14 amino acids and a second composed of 28 amino acids.
Regulatory Mechanisms of Somatostatin Expression - PMC
In mammals, somatostatin originates from pre-prosomatostatin and is processed to a shorter form, i.e., somatostatin-14, and a longer form, i.e., somatostatin-28. The two peptides repress growth hormone secretion and are involved in the regulation of glucagon and insulin synthesis in …