Azacitidine (5-azacytidine) is a chemical analogue of the cytosine nucleoside present in DNA and RNA. 1,2 It induces antineoplastic activity by inhibiting DNA methyltransferase at low doses …

2016年8月27日 · 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to …

5-azacytidine is an N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used …

2002年8月5日 · Christman, J. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

This substance was considered by a previous Working Group, in October 1980, under the title 5-azacytidine (IARC, 1981). Since that time, new data have become available, and these have …

Additional Information From Chemocare.com About 5-Azacitidine Self-Care Tips. Drink at least two to three quarts of fluid every 24 hours, unless you are instructed otherwise. You may be at …

2024年10月9日 · Azacitidine. Generic name: azacitidine (oral/injection) [ ay-za-SYE-ti-deen ] Brand names: Onureg, Vidaza Dosage forms: injectable powder for injection (100 mg), oral …

5-azacytidine (5-azaC) not only prolongs the survival of patients with intermediate 2 and high-risk myelodysplastic syndrome (MDS), 1, 2 but also leads to improvements in cytopenias, reduces …

5-Azacytidine is a pyrimidine nucleoside analog that has been discovered more than 40 years ago. Despite remarkable responses in the treatment of acute myeloid leukemias in the 1970s …

5-Azacytidine is a compound that is similar to cytidine and is known for its cancerostatic, bacteriostatic, and mutagenic properties. It is incorporated into RNA and DNA, disrupting …