2017年10月3日 · Previously treated patients: a target AUC of 4-6 mg/mL•min using single agent Carboplatin Inj appears to provide the most appropriate dose range. For patients who previously DID NOT receive chemotherapy (untreated), a target AUC of 7 (range: 6-8) mg/mL per minute has been recommended when carboplatin is used alone.

This carboplatin dosing calculator uses the Calvert method to calculate the total carboplatin dose needed to achieve a given AUC (area under the free carboplatin plasma concentration versus time curve) while taking into account renal function.

Carboplatin dose using Calvert formula. Target AUC Area under the curve. Reflects target concentration of carboplatin in the blood measured in mg/ml/min. Values between 4 to 7 are commonly used. The clearance of carboplatin is closely related to glomerular filtration rate (GFR).

2023年3月15日 · Detailed Carboplatin dosage information for adults. Includes dosages for Ovarian Cancer; plus renal, liver and dialysis adjustments.

2024年6月12日 · This carboplatin calculator (carboplatin dose calculator) estimates your total carboplatin dose (in mg) using the Calvert formula). The evaluations are based on a person's creatinine clearance calculations (found using the Cockcroft - Gault equation) and the targeted carboplatin AUC value.

2023年4月4日 · Carboplatin is injected slowly into a vein by a healthcare provider over 15 minutes or longer. carboplatin is usually given once every 4 weeks. Doses are based on body surface area (height and weight) and kidney function.

Previously treated patients: a target AUC of 4-6 mg/mL•min using single agent Carboplatin Inj appears to provide the most appropriate dose range. For patients who previously DID NOT receive chemotherapy (untreated), a target AUC of 7 (range: 6-8) mg/mL per minute has been recommended when carboplatin is used alone.

This calculator calculates carboplatin doses via the Calvert formula with a target Area Under the Curve (AUC), using three options for kidney function: Directly Measured GFR (mGFR)* Body Surface Area (BSA) Adjusted eGFR CKD-EPI **

2024年11月23日 · There are several methods to calculate the dose of carboplatin, including the Calvert formula, which takes into account the patient’s creatinine clearance and the target area under the concentration-time curve (AUC).

2024年6月10日 · Carboplatin Dosage and Administration General. Consult specialized references for procedures for proper handling and disposal of antineoplastics. Carboplatin is considered a moderate antiemetic risk antineoplastic (i.e., 30–90% incidence of emesis without antiemetics).