2021年2月15日 · Cardiac fibroblasts are the primary cell type responsible for deposition of extracellular matrix in the heart, providing support to the contracting myocardium and …

2022年11月14日 · In this Review, we describe the mechanical role of cardiac fibroblasts during cardiac development, with an emphasis on the capacity of fibroblasts to ‘perceive’ mechanical …

2009年12月4日 · Cardiac fibroblasts respond to a wide range of different stimuli during cardiac development and disease, including hypoxia, as well as changes in chemical and mechanical …

Cardiac fibrosis remains an important health concern, but the study of fibroblast biology has been hindered by a lack of effective means for identifying and tracking fibroblasts. Recent advances …

2016年3月18日 · Cardiac fibroblasts comprise an essential cell type in the heart that is responsible for the homeostasis of the extracellular matrix; however, upon injury, these cells …

2017年4月24日 · As our understanding of cardiac fibroblasts becomes more defined and refined, so does the potential to develop new therapeutic strategies to control fibrosis and adverse …

Cardiac fibroblasts are a major cell population of the heart and are characterized by their capacity to produce extracellular matrix (ECM). In hearts subjected to pressure overload, excessive …

2019年5月20日 · Nature Communications - Cardiac fibroblasts (CFs) play critical roles in heart development, homeostasis, and disease. Here the authors efficiently differentiate human …

2024年8月2日 · Cardiac fibroblasts play a pivotal role in maintaining heart homeostasis by depositing extracellular matrix (ECM) to provide structural support for the myocardium, …

2023年9月9日 · This review provides an overview of the current understanding of heterocellular electrical communication in the heart. Although cardiac fibroblasts were initially thought to be …