2016年3月17日 · We developed a physiological microenvironment of semisynthetic origin, called gelatin methacryloyl (GelMA)-based hydrogels, which combine the biocompatibility of natural matrices with the...

2010年7月1日 · Here, we demonstrate gelatin methacrylate (GelMA) as an inexpensive, cell-responsive hydrogel platform for creating cell-laden microtissues and microfluidic devices. Cells readily bound to, proliferated, elongated, and migrated both when seeded on micropatterned GelMA substrates as well as when encapsulated in microfabricated GelMA hydrogels.

Hasani-Sadrabadi and colleagues developed an injectable alginate-based adhesive hydrogel that encapsulated aggregates of gingival mesenchymal stem cells and osteoconductive hydroxyapatite microparticles. In a rat model of peri-implantitis, the hydrogel …

Cell-laden hydrogels with biodegradable matrices could be promising in tissue regeneration and drug delivery due to their unique features, such as biocompatibility and native ECM-like properties. Examples include injectable microgels, which are loaded with bone marrow-derived mesenchymal stem cells in GelMA hydrogel droplets.

Cell-laden injectable hydrogels can be utilized for tissue regeneration in a noninvasive way. This article reviews the recent advances and future opportunities of cell-laden injectable hydrogels and their functions in tissue engineering.

This study presents an injectable cell-laden hydrogel system based on silk acid, a carboxylated derivative of natural silk fibroin, which exhibits promising applications in biomedicine. The hydrogel is produced under physiological conditions (37 °C and pH 7.4) via physical crosslinking.

2024年2月2日 · Deshmukh and co-workers demonstrated a method based on acoustically activated capillaries for generating parallel cell bundles within hydrogel fibers, which paves the way for continuous production of structured cell-laden hydrogel fibers.

2014年7月1日 · To optimize the scaffold properties and its compatibility with native niche, cell-laden hydrogel is an appealing option that helps engineering potential tissue constructs with biomimetic...

2017年7月15日 · Cell-laden hydrogel systems have emerged as a promising tissue-engineering platform to address this issue. In this article, we describe the fundamental problems encountered in this field and review recent progress in designing cell-hydrogel constructs for promoting the reestablishment of osteochondral/cartilage tissues.

2020年3月1日 · Hydrogel plays a vital role in cell-laden three dimensional (3D) bioprinting, whereas those hydrogels mimic the physical and biochemical characteristics of native extracellular matrix (ECM).