2024年7月25日 · MRI is the modality of choice for assessing corticobasal degeneration, although similar findings can, only to a certain degree, be seen on CT. MRI. Typical findings include 1,2: asymmetric cortical atrophy. superior parietal lobule: most constant feature. perirolandic gyri. precentral gyri. postcentral gyri. superior frontal gyri

Corticobasal degeneration (CBD) is a neurodegenerative disorder characterized by the presence of cortical and striatal hyperphosphorylated 4-repeat (4R) tau deposition, especially astrocytic plaques and thread-like lesions, in the white matter and gray matter, accompanied by neuronal loss in the cortical regions and substantia nigra .

MRI scans are key in diagnosing and understanding Corticobasal Syndrome (CBS). They show distinct signs with T1-weighted and T2-weighted sequences. They also show brain atrophy and changes in white matter.

2025年2月5日 · Corticobasal ganglionic degeneration (CBD) is a rare and progressive neurodegenerative disorder with diverse clinical and pathological features. The most common clinical presentation, corticobasal syndrome, includes asymmetric limb rigidity, Parkinsonism, dystonia, and cortical dysfunction, such as apraxia or sensory deficits. Pathologically, CBD is …

Magnetic resonance imaging (MRI) is key in spotting corticobasal degeneration (CBD). It doesn’t need surgery and shows the brain clearly. This helps doctors see changes in CBD and tell it apart from other brain diseases. Using MRI for CBGD has …

Our review of MRI findings demonstrates that it is possible to detect asymmetrical parietal atrophy, thus supporting the clinical diagnosis of corticobasal degeneration. It is essential to be aware of the disease and alert for asymmetries in order to discern the more involved side.

Clinical records were reviewed and quantitative volumetric analysis of symmetric atrophy on head MRI using atlas based parcellation was performed. Subjects were classified as S-CBD if no differences had been observed between right- and left-sided cortical or …

Pathologic and MR findings of a patient with cortico-basal degeneration who subsequently underwent autopsy. A, Three-dimensional reconstructed surface anatomic scan (2000/25/2 [repetition time/echo time/excitations]), obtained for a better view of the surface cortical anatomy, shows dilatation of convexity sulci (arrow), especially the right side.

MRI of patients with CBD revealed significantly greater T2-weighted signal hypointensity in the putamena and globi pallidi, and ventricular enlargement. When specifically sought, asymmetrical cortical atrophy was identified in 5 of 8 CBD patients.

Objective: To characterize brain fluorodeoxyglucose (FDG) PET-MRI findings in patients with corticobasal syndrome (CBS) and evaluate its utility in early diagnosis of Corticobasal Degeneration (CBD)