2021年8月6日 · prevention of cerebral edema. Previously, the following measures were recommended to avoid cerebral edema in patients at risk: (1) Don't drop the glucose too fast or too low. Also avoid reducing the glucose below <200 mg/dL (<11 mM). (2) Avoid hypotonic fluids (there is no rush in reducing the tonicity).

Diabetic ketoacidosis (DKA) is associated with a high mortality rate, especially if cerebral edema develops during the disease course. It is rarer and more severe in adults than in children. We present cases of two patients with cerebral edema‐related DKA.

2022年8月17日 · Cerebral injury (cerebral edema) is an uncommon but potentially devastating consequence of diabetic ketoacidosis (DKA). This complication is far more common among children with DKA than among adults. Children presenting with more severe DKA (higher blood urea nitrogen levels and more severe acidosis and hypocapnia) are at greatest risk [ 1-4 ].

Cerebral edema is the leading cause of death in children presenting in diabetic ketoacidosis and occurs in 0.2 to 1% of cases. The osmolar gradient caused by the high blood glucose results in water shift from the intracelluar fluid (ICF) to the extracellular fluid …

The issue of how best to prevent or treat DKA related cerebral edema is significant, given that the incidence of Type I diabetes mellitus is increasing worldwide and because DKA is its most common complication, occurring in 25–40% of these children. Published literature suggests that the use of hypertonic saline appears to be increasing in ...

Cerebral edema is described as occurring in DKA in 0.4 to nearly 5% of cases, due to referral bias and variable diagnostic criteria. Mortality in the context of cerebral edema is 21% with morbidity rates reported of 10-26%. Cerebral edema typically occurs 4-12 hrs after treatment has been started, but it has been described to occur

Neurologic deterioration associated with cerebral edema (CE) in diabetic ketoacidosis (DKA) is typically sudden in onset, progresses rapidly and requires emergent treatment. The utility of brain imaging by head computed tomography (CT) in decisions to …

2019年2月11日 · Are you sure your patient has diabetic ketoacidosis–related cerebral edema? What are the typical findings for this disease? Cerebral edema is a potentially life-threatening complication of...

2004年7月1日 · Cerebral dysfunction in DKA is usually a manifestation of metabolic derangement, but cerebral edema (CE) arises in ∼1% of episodes and is a complication that frequently causes irreversible brain damage and death (1–7).

2014年2月21日 · Cerebral edema is the most feared emergent complication of pediatric diabetic ketoacidosis. Fortunately, it is relatively rare, but the rarity can lead to some confusion when it comes to its management.