Hippuric acid (Gr. hippos, horse, ouron, urine) is a carboxylic acid and organic compound. It is found in urine and is formed from the combination of benzoic acid and glycine. Levels of hippuric acid rise with the consumption of phenolic compounds (such as in fruit juice, tea and wine).

Hippuric Acid is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food. Increased urine hippuric acid content may have antibacterial effects.

Hippurate is a glycine conjugate of benzoic acid formed in the mitochondria of the liver and kidneys. Bacteria also convert certain food components (polyphenols) into hippurate. Hippurate is also derived from the metabolism of quinic acid and/or shikimic acid. Hippurate is a bacterial product of phenylalanine metabolism. What are polyphenols?

This literature highlights the utility of hippuric acid in urine and plasma as a plausible hallmark of frailty, related to low fruit and vegetable intake and changes in gut microflora. Keywords: Aging; Gut microbiota; Hippurate; Metabolism.

Hippurate is the glycine conjugate of benzoic acid that can be derived from the bacterial metabolism of phenylalanine, chlorogenic acid, and catechins. You might find these chapters and articles relevant to this topic. Griet Glorieux, ... Raymond Vanholder, in Critical Care Nephrology (Second Edition), 2009.

Hippuric acid, which is Benzoylamino-acetic acid, is used for salt formation with Methenamine to yield a 1:1 salt. Even as the therapeutic dose of Methenamine is already high with a maximum daily dose of Methenamine of 880 mg and a low molar mass of Methenamine of 140 g/mol, hippurate with a high molar mass of 179 g/mol was chosen as salt ...

2023年2月24日 · Hippuric acid is the glycine conjugate of benzoic acid. In human beings, it was first studied in the fields of occupational medicine and toxicology because it represents the final metabolite of toluene detoxification metabolic pathways [4].

Aim of this study was to evaluate the biotransformation of simple phenols after ingestion of edible fruits and mixed food. It was analyzed hippuric acid in urine as biomarker of conjugation in the liver cells of glycine with aromatic phenolic acids ...

Hippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic acid.

2023年10月2日 · Hippuric acid, or N-benzoylglycine, is an amino acid derivative found in the urine of herbivorous animals. The name is derived from Greek hippos (horse) and ouron (urine). In 1829, the pioneering German chemist Justus von Liebig so named it because his research on the compound concentrated on horse urine.