Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome of excessive immune activation. It most frequently affects infants from birth to 18 months of age, …

In adults, soluble IL-2 receptor has been found to be a very sensitive marker for HLH, demonstrating 100% sensitivity for ruling out HLH below a cutoff of 2400 U/mL and optimal …

2024年6月5日 · HLH causes a hemorrhagic form of DIC with increased risk of bleeding due to low fibrinogen levels. Prior to lumbar puncture, consider checking a fibrinogen level, coagulation …

2019年6月6日 · Hemophagocytic lymphohistiocytosis (HLH) has become more widely recognized in adults, with all ages affected. Patients often suffer from recurrent fever, cytopenia, liver …

Hemophagocytic lymphohistiocytosis (HLH) is a condition that occurs when your immune system abnormally overreacts. Your immune system defends your body from things that make you …

To determine the effectiveness of the therapy, clinical and disease-specific HLH markers need to be evaluated on a regular basis. Clinical markers that should be evaluated daily include …

Diagnosing hemophagocytic lymphohistiocytosis can be difficult. Find an HLH diagnostic algorithm, what genetic tests to order and expert advice for physicians.

Recently, the subpopulation of CD8 + CD38 high /HLA-DR + cells was investigated as a diagnostic marker for HLH in a cohort of 43 pediatric patients (median age 2.6 years) without …

2020年11月3日 · Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation characterized by clinical signs and symptoms of extreme inflammation. two forms: …

2024年7月19日 · Hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disease of normal but overactive histiocytes and lymphocytes that commonly appears in infancy, …