Understanding the mechanism of IL-1β secretion - PMC
Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine that is crucial for host-defence responses to infection and injury [1]. It is also the best characterised and most studied of the …
Interleukin 1beta - an overview | ScienceDirect Topics
Interleukin-1 (IL-1) is a cytokine which governs inflammatory responses by binding IL-1 α and β agonist with its receptor IL-1R (Vigers et al., 1997). IL-1β is synthesized by inflamasome …
Alpha Cells, The Main Source of IL-1β in Human Pancreas
Interleukin-1β (IL-1β) is known to trigger beta cell dysfunction in vitro and could potentially play a role during the pathogenesis of type 1 diabetes and type 2 diabetes. However, several clinical …
IL1B interleukin 1 beta [Homo sapiens (human)] - Gene - NCBI
5 天之前 · Title: Effect of α7 nAChR-autophagy axis of deciduous tooth pulp stem cells in regulating IL-1β in the process of physiological root resorption of deciduous teeth. Interleukin …
Interleukin-1 (IL-1) Pathway | Science Signaling - AAAS
2010年1月19日 · IL-1–type cytokines are major mediators of innate immune reactions, and blockade of the founding members IL-1α or IL-1β by the interleukin-1 receptor antagonist (IL …
IL-1β promotes adipogenesis by directly targeting adipocyte
2024年9月11日 · In vitro, IL-1β potently promotes adipogenesis in murine and human adipose-derived stem cells. This effect is exclusive to early-differentiation-stage cells, in which the …
The Role of Interleukin 1β in the Pathogenesis of Lung Cancer.
IL-1β is activated when a specific inflammasome, nucleotide-binding domain-like receptor protein 3, induces cleavage of pro-IL-1β into its active form. Nucleotide-binding domain-like receptor …
IL-1β is an innate immune sensor of microbial proteolysis
Interleukin-1β (IL-1β) is a key proinflammatory cytokine that drives antimicrobial immune responses. IL-1β is aberrantly activated in autoimmune diseases, and IL-1β inhibitors are used …
IL-1β, an important cytokine affecting Helicobacter pylori …
2023年1月1日 · IL-1β is a multi-effector cytokine and affects growth, angiogenesis, proliferation, metastasis and invasion of gastric cancer cells. (1) IL-1β recruits myeloid derived suppressor …
IL-1β-induced epithelial cell and fibroblast transdifferentiation ...
2024年10月22日 · IL-1β, a pro-inflammatory cytokine involved in IL-1 signaling, induces the transdifferentiation of LY6D+ club cells and IDO1+ fibroblasts from primary epithelial cells and …
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