Fibrous dysplasia is a benign (noncancerous) bone condition in which abnormal fibrous tissue develops in place of normal bone. As these areas of fibrous tissue grow and expand over time, they can weaken the bone — causing it to fracture or become deformed.

Healthcare providers classify fibrous dysplasia based on how many of your bones it affects: Monostotic fibrous dysplasia affects only one bone. Polyostotic fibrous dysplasia affects multiple bones. How common is it? Fibrous dysplasia is rare.

It is a rare bone disease characterized by the replacement of normal elements of the bone by fibrous connective tissue, [3] which can cause very painful swellings and bone deformities, and make bone abnormally fragile and prone to fracture.

2023年7月24日 · Fibrous dysplasia is a typically benign bone lesion characterized by intramedullary fibro-osseous proliferation secondary to altered osteogenesis. The polyostotic form often presents in childhood. Malignant transformation is rare, and remote radiation therapy has been reported as a risk factor.

Fibrous dysplasia presents in monostotic and polyostotic forms. The more common monostotic form affects one bone and accounts for approximately 70% to 85% of cases.

2024年12月23日 · Fibrous dysplasia (FD) is a developmental benign medullary fibro-osseous process characterized by the failure to form mature lamellar bone and arrest as woven bone that can be multifocal. It can affect any bone and occur in a monostotic form involving only one bone or a polyostotic form involving multiple bones.

2024年9月30日 · monostotic fibrous dysplasia in the upper extremity with low risk of fracture typically not recommended due to poor outcomes including high rate of graft resorption, fracture, and need for subsequent reoperation

What is fibrous dysplasia? Fibrous dysplasia is a long-term (chronic) problem in which scarlike tissue grows in place of normal bone. It is not cancer. It often results in one or more of these: Bone deformity. Brittle bones. Pain. Uneven growth of bones. Any bone can be affected. More than one bone can be affected at any one time.

2020年9月28日 · A diagnosis of fibrous dysplasia is based upon identification of characteristic symptoms, a detailed patient history, a thorough clinical evaluation and a variety of specialized tests. Individuals with mild forms of monostotic FD may be diagnosed incidentally when receiving an x-ray for another reason.

2020年1月2日 · The trabeculae in fibrous dysplasia are composed of woven bone with various phases of mineralization. Mature lamellar bone can be seen at the periphery but should not be part of the lesion itself.