Gossypol (/ ˈ ɡ ɒ s ə p ɒ l /) is a natural phenol derived from the cotton plant (genus Gossypium). Gossypol is a phenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. It is a yellow pigment. The structure exhibits atropisomerism, with the two enantiomers having different biochemical properties. [1]

Gossypol is a pigment that is found in certain plants, including the cotton plant. It is found in the seeds, stem, and roots. It's used as medicine. Gossypol interferes with sperm development...

2024年8月16日 · Gossypol is a nonsteroidal compound that inhibits sperm production and motility in a variety of male animals and in humans, but it does not affect sex hormone levels or libido. Gossypol exerts its contraceptive action by inhibiting enzyme systems that play a crucial role in energy metabolism in sperm and spermatogenic cells.Coutinho 2002, Wang 2009

2024年11月18日 · Gossypol is a naturally occurring polyphenolic compound derived primarily from the seeds and leaves of the cotton plant (Gossypium species). It has been studied for various pharmacological effects, including anti-inflammatory, anti-tumor, and …

2023年12月15日 · Gossypol, a polyphenolic aldehyde derived from cottonseed plants, has seen a transformation in its pharmaceutical application from a male contraceptive to a candidate for cancer therapy.

Gossypol is a substance that is found in the cotton plant. It is removed from the seeds and used for medicine. Men take gossypol for birth control. Women take it for disorders of the uterus including endometriosis, abnormal bleeding, and cancer; as well as for ovarian cancer. Gossypol is also used for treating HIV / AIDS.

Gossypol, a natural polyphenolic compound derived from the seeds, roots, and stems of cotton (Gossypium hirsutum L.), was first used as a male contraceptive agent.

2009年7月9日 · Gossypol, a natural compound present in cottonseeds, displays antiproliferative and pro-apoptotic effects against various cancer cells. The (-)-gossypol enantiomer is a more potent inhibitor of cancer cell growth. Here, the molecular mechanisms of apoptosis induced by (-)-gossypol were studied in human prostate cancer cells.

Gossypol is a versatile molecule with an abundance of biological properties. It has the potential for use in the development of drugs for disorders as varied as resistant tumors, HIV, malaria, and psoriasis.

Gossypol consists of two highly oxygenated forms of cadinene (hemi-gossypol) joined together by a binaphthyl linkage to form a potent toxin that affords an unparalleled level of insect resistance to cotton plants, Gossypium barbadense, and related species.