Sulfonylureas: Just Stop - Medscape
2018年8月13日 · Patients taking sulfonylureas as second-line therapy—replacing rather than adding on to metformin—had increased risks for myocardial infarction, all-cause mortality, and severe hypoglycemia ...
Toxicology of Oral Antidiabetic Medications - Page 2 - Medscape
The goal of sulfonylurea overdose management is the return of euglycemia, with either dextrose supplementation or reduction of insulin secretion. Activated charcoal is expected to bind the ...
Sulfonylureas as Street Drugs: Hidden Hypoglycemia Cause
2023年5月8日 · SEATTLE ― Taking sulfonylureas sold as "street Valium" can lead to severe hypoglycemia that may result in emergency department (ED) visits, the latest of a handful of case reports suggests. ...
Are Fluoroquinolones Safe in Sulfonylurea Users? - Medscape
2024年5月31日 · TOPLINE: Fluoroquinolones don't increase the risk for severe hypoglycemia compared with amoxicillin in older patients with diabetes treated with second-generation sulfonylureas, but caution is ...
SGLT2 Inhibitors Protective Against Retinopathy in T2D - Medscape
2024年1月23日 · During the 5-year study period, 159,965 patients were treated with SGLT2 inhibitors, 304,383 received dipeptidyl peptidase-4 (DPP-4) inhibitors, 108,420 took pioglitazone, and 189,618 received ...
Is Glimepiride a Safer Sulfonylurea for Type 2 Diabetes? - Medscape
2022年12月22日 · People with type 2 diabetes treated with metformin plus a sulfonylurea with high affinity for cardiac mitochondrial adenosine triphosphate–sensitive potassium (mitoK ATP) channels, such as ...
Sulfonylureas for Diabetes Still Have a Role; Cost a Big Factor
2017年6月10日 · A recent study reported that sulfonylureas are still used by 31% of patients with diabetes in the United States, and rates of use are even higher in Europe — 41% to 45% of patients in the United ...
All-Cause Mortality Risk With Sulfonylurea Use - Medscape
2013年9月25日 · In total, there were 16.9 deaths per 1000 person-years in the metformin/sulfonylurea patients and 7.3 deaths per 1000 person-years in the metformin/DPP-4 group. This translated into a 35% ...
Sulfonylureas Work Long-Term in Permanent Neonatal Diabetes
2018年6月18日 · Moreover, assessment of long-term safety is also important because sulfonylureas are associated with hypoglycemia in people with type 2 diabetes and the dose used to treat KCNJ11 permanent ...
FDA Safety Changes: Arixtra, Sulfonylureas, Tobramycin - Medscape
2009年10月7日 · The FDA approved sulfonylurea class safety labeling revisions for glipizide and glipizide extended-release tablets, micronized glyburide tablets, glipizide/metformin HCl tablets, and glyburide ...