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How I prescribe continuous renal replacement therapy
2021年1月2日 · Blood flow rate prescription varies with modality. For CVVHD, the blood flow rate should be at least twice the dialysate flow rate to maximise the plasma to dialysate concentration gradient. For CVVH, blood flow rate should be titrated to prevent a filtration fraction (plasma water removal to plasma flow ratio) > 25%.
Optimal Mode of clearance in critically ill patients with Acute …
2012年10月24日 · Introduction Among critically ill patients with acute kidney injury (AKI) needing continuous renal replacement therapy (CRRT), the effect of convective (via continuous venovenous hemofiltration [CVVH]) versus diffusive (via continuous venovenous hemodialysis [CVVHD]) solute clearance on clinical outcomes is unclear. Our objective was to evaluate the …
How to Prolong Filter Life During Continuous Renal Replacement …
2022年3月22日 · Theoretically, CVVH has a better clearance of medium-sized solutes than CVVHD, but in practice it has been suggested that CVVHD provides equivalent clearance . Although many studies have compared different modes of CRRT to each other for solute clearance or mortality, filter life was seldom measured as an outcome [ 7 ].
Continuous haemofiltration in the intensive care unit
2000年10月20日 · This CVVH-based approach to the treatment of acute renal failure (ARF) has now been extended to include high-volume haemofiltration [7,14] and more complex circuit modifications [15,16] that are aimed at increasing blood purification in septic shock or at removing excess plasma water during cardiac surgery .
The effects of continuous venovenous hemofiltration on …
2006年10月27日 · Introduction The mechanism of coagulation activation during continuous venovenous hemofiltration (CVVH) has not yet been elucidated. Insight into the mechanism(s) of hemostatic activation within the extracorporeal circuit could result in a more rational approach to anticoagulation. The aim of the present study was to investigate whether CVVH using …
Myoglobin clearance with continuous veno-venous hemodialysis …
2020年11月11日 · Convection-based RRT techniques such as continuous veno-venous hemofiltration (CVVH) require higher extracorporeal circuit blood flow than diffusion-based ones, which is related to hemoconcentration at the dialyzer. Therefore, RCA during CVVH is hardly possible due to the high risk of citrate accumulation.
Citrate anticoagulation versus systemic heparinisation in …
2014年8月16日 · Introduction Because of ongoing controversy, renal and vital outcomes are compared between systemically administered unfractionated heparin and regional anticoagulation with citrate-buffered replacement solution in predilution mode, during continuous venovenous hemofiltration (CVVH) in critically ill patients with acute kidney injury (AKI). Methods In this …
Hypophosphatemia during continuous veno-venous …
2013年9月19日 · Introduction The primary aim of this study was to determine whether hypophosphatemia during continuous veno-venous hemofiltration (CVVH) is associated with the global outcome of critically ill patients with acute kidney injury (AKI). Methods 760 patients diagnosed with AKI and had received CVVH therapy were retrospectively recruited. Death …
Regional citrate anticoagulation in cardiac surgery patients at high ...
2012年6月27日 · Introduction Regional citrate anticoagulation (RCA) is a valid option in patients at high risk of bleeding who are undergoing continuous renal replacement therapy (CRRT). The aim of this study was to evaluate, in critically ill patients with severe acute kidney injury following cardiac surgery, the efficacy and safety of RCA-continuous veno-venous hemofiltration …
Management of sodium disorders during continuous haemofiltration
2010年5月27日 · If CVVH is needed, the Na + concentration in the replacement fluid (usually 140 mmol/l) needs to be adjusted in order to avoid rapid changes of the serum Na + concentration. In the present paper we provide some guidance on how to make these adjustments for CVVH. The same principle could be applied for continuous haemo dialysis or diafiltration.