Hyperferritinemia—A Clinical Overview - PMC
High ferritin, hyperferritinemia, may indicate increased iron stores, but is more commonly seen upon acute phase reactions and as a result of ferritin being released from damaged cells such as hepatocytes in liver disease [5].
Hyperferritinaemia: what is it, symptoms and treatment - Top …
2018年1月15日 · Hyperferritinaemia is a condition in which the body has an excess of ferritin – a protein involved in storing iron, due to its ability to bind to it. Excess ferritin is a marker of iron overload diseases, such as haemochromatosis. Whether associated with another disease or not, hyperferritinaemia can have one serious complication: cataracts.
Extreme Hyperferritinemia: Causes and Prognosis - PMC
Hyperferritinemia is usually defined by a level of total serum ferritin (TSF) exceeding 200 µg/L in women and 300 µg/L in men [1]. There are many causes of hyperferritinemia, including alcohol intake, liver disease, infection, cancer, chronic inflammation, or metabolic syndrome [2].
Hyperferritinemia - CMAJ
2021年10月4日 · Clinicians obtain ferritin levels when they suspect iron deficiency or overload; they may also obtain ferritin levels during the work-up of some hematologic or autoimmune conditions. 1 – 4 Levels may be elevated in many chronic conditions (Box 1) or during acute illness, which can confound interpretation. 2 Levels that return to normal after res...
Interpreting raised serum ferritin levels | The BMJ
2015年8月3日 · Normal serum ferritin levels vary between laboratories but generally concentrations >300 µg/L in men and postmenopausal women and >200 µg/L in premenopausal women are regarded as elevated. 1 Low ferritin values provide absolute evidence of iron deficiency. 2 Raised levels often indicate iron overload, but they are not specific, as ferritin is an...
Elevated serum ferritin What should GPs know? - RACGP - The …
After exclusion of hereditary haemochromatosis, investigation of elevated serum ferritin involves identifying alcohol consumption, metabolic syndrome, obesity, diabetes, liver disease, malignancy, infection or inflammation as causative factors.
Evaluation of hyperferritinemia causes in rheumatology practice: …
Hyperferritinemia may develop due to various reasons such as inflammation, infection, or malignancy. The purpose of the study to explore the prevalence and to figure out the causes of general hyperferritinemia and extreme hyperferritinemia as ...
High Serum Ferritin results are a common finding in primary care. Because ferritin is an acute phase reactant this is usually due to inflammation, malignancy or liver disease. It can less commonly be associated with iron overload.
Ferritin test - Mayo Clinic
2023年12月19日 · Iron deficiency can cause anemia. If a ferritin test shows high ferritin levels, it most often means swelling in the body, called inflammation. Conditions that can cause inflammation include liver disease, rheumatoid arthritis and other inflammatory conditions, and overactive thyroid, called hyperthyroidism.
Update in Hyperferritinemic Syndromes: Recognition and …
Hyperferritinemia, defined as serum ferritin above 500 ng/mL, can be seen in hemophagocytic lymphohistiocytosis (HLH) and its secondary subcategory, macrophage activation syndrome (MAS), catastrophic antiphospholipid syndrome (CAPS), septic shock, adult-onset Still’s Disease (AOSD), and more recently multi-inflammatory syndrome related to ...