Metronidazole
- 已发布: 2023/06/26
- Authors: Connor B. Weir, Jacqueline K. Le
- 附属关系: Michigan State University/Mclaren, Desert Regio…
Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. It is cytotoxic to facultative anaerobic microorganisms.Metronidazole: An overview - UpToDate
2022年12月1日 · It is approved by the US Food and Drug Administration for the treatment of anaerobic and protozoal infections. Metronidazole exerts its antimicrobial effects through the …
Metronidazole: Uses, Interactions, Mechanism of …
Metronidazole is a nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
Metronidazole - Wikipedia
Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory …
Metronidazole: Mechanism, Activity, Pharmacokinetics, and …
2024年10月23日 · Explore the comprehensive insights into metronidazole's mechanism, activity spectrum, pharmacokinetics, and potential drug interactions.
Metronidazole - PubMed
Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. It is cytotoxic to facultative …
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Metronidazole - an overview | ScienceDirect Topics
Metronidazole is a basic compound with a pKa value of 2.62 and is moderately soluble in water (approximately 10 mg/mL at 25°C) at pH 2.5 to 8.0; the pH of the IV infusion is 5.8. 60,61 Oral …
Metronidazole: Package Insert / Prescribing Info - Drugs.com
2024年10月29日 · Metronidazole package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.
Metronidazole - Antimicrobe
Metronidazole produces concentration-dependent killing Pharmacokinetics: Half-life: 8h (mean); Volume of distribution: 0.51 to 1.1L/kg (adults); Renal clearance: 8-12ml/min; Bioavailability: …
The mechanism of action of Metronidazole involves four main steps which lead to the intracellular formation of essential redox intermediate metabolites[18]. In the first two phases, the …